GetFundedUSA › Grants › General › Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)
Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)
General · National Institutes of Health · Nationwide
This is a National Institutes of Health cooperative agreement funding research into how human behaviors affect oral and systemic health in people with chronic conditions, open to eligible U.S.-based organizations, with an application deadline of July 5, 2029.
This funding opportunity, sponsored by the National Institutes of Health (NIH), supports research into the causes of human behaviors and how those behaviors affect oral and systemic health in people with chronic conditions. It is structured as a Cooperative Agreement (U01), meaning NIH staff are expected to be substantially involved in the funded project, not just providing money and stepping away.
The Notice of Funding Opportunity (NOFO) invites applications proposing causal hypotheses that may involve biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychological, or comorbidity factors — alone or in combination — that trigger behaviors linked to oral-systemic health outcomes. These impacts can be direct or more distal in nature. NIH also welcomes applications aimed at developing or refining such causal hypotheses, rather than only testing fully formed ones. Notably, this opportunity does not allow clinical trials.
While this is a federal research grant rather than a typical small-business award, it may be relevant to small research organizations, academic-affiliated businesses, or health research entities that qualify as applicants under NIH rules. Eligible applicants must review Section III of the NOFO for specific eligibility criteria. Foreign organizations, non-domestic components of U.S. organizations, and foreign components of any kind are explicitly not eligible to apply.
The deadline listed for this opportunity is July 5, 2029, though applicants should confirm current deadlines directly on the official Grants.gov listing, as NOFOs can have multiple cycles or updates. No specific award floor, ceiling, or funding amount is provided in the available data, so applicants should consult the official NOFO for financial details. Anyone considering applying should carefully read the full NOFO for eligibility, budget, and submission requirements before proceeding.
Who qualifies
How to apply
Questions people ask
Is this a grant or a loan?
It is a cooperative agreement (U01), a type of federal grant funding mechanism, not a loan.
Do I have to repay this funding?
No, cooperative agreements are not repaid, but they involve significant NIH programmatic involvement.
Who is eligible to apply?
Eligibility is detailed in Section III of the NOFO; foreign organizations and foreign components are not eligible.
Can foreign organizations apply?
No, non-domestic entities, non-domestic components of U.S. organizations, and foreign components are not allowed.
How much funding is available?
The specific award floor, ceiling, or amount is not provided in the available data — confirm at the official source.
What is the application deadline?
The deadline listed is July 5, 2029, at 12:00 AM EDT.
Where do I apply?
Applications are submitted through Grants.gov at https://www.grants.gov/search-results-detail/360160.
What does this funding support?
It supports research into causal factors behind human behaviors and their oral-systemic health impacts among people with chronic conditions.
Are clinical trials allowed under this opportunity?
No, this NOFO specifies that clinical trials are not allowed.
Is this funding taxable?
The data does not specify tax treatment; confirm at the official source.
Which states are eligible?
The opportunity is open to applicants in all states, though other eligibility rules still apply.
What agency runs this program?
The National Institutes of Health (NIH) sponsors this funding opportunity.
Can I propose new hypotheses rather than test existing ones?
Yes, applications developing or refining causal hypotheses are encouraged, not just those testing established ones.
Opportunity number: PAR-27-057. Source: grants.gov. GetFundedUSA is independent and not affiliated with National Institutes of Health; always confirm current deadlines, amounts and eligibility on the sponsor's own page before applying.