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NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
R&D / Tech · National Institutes of Health · Nationwide
The NIH Small Business Technology Transfer Grant, or Parent STTR R41/R42, is a federal grant from the National Institutes of Health that helps U.S. small businesses partnered with nonprofit research institutions fund feasibility studies and research and development toward commercial products. It's open to eligible small businesses in all U.S. states, with applications due by April 5, 2027.
The NIH Small Business Technology Transfer Grant, also known as the Parent STTR (R41/R42) with Clinical Trial Optional, is a federal grant program funded by the National Institutes of Health. It is designed to help United States small business concerns (SBCs) that partner with a nonprofit research institution move scientific innovations toward the marketplace.
Under the STTR program, funding is provided in two phases: the R41 phase supports feasibility studies to test the scientific and technical merit of an idea, while the R42 phase supports later-stage research and development work needed to build toward a commercial product. This structure allows small businesses to receive support at different stages of maturity for their innovation.
This is a grant, not a loan, meaning funds generally do not need to be repaid if used according to the award terms. It falls under the research and technology (R&D) funding category and is open to eligible small businesses in all U.S. states, since the eligible_states value is listed as ALL.
Because this is a federal SBIR/STTR-style opportunity, applicants must partner with a nonprofit research institution as part of the collaborative structure required by the STTR mechanism. Only U.S. small business concerns as defined by the Small Business Administration may apply; foreign organizations and non-domestic components of U.S. organizations are not eligible.
The deadline listed for this opportunity is April 5, 2027. Specific award amounts, funding floors, and ceilings were not provided in the available data, so applicants should confirm current award amounts and full program requirements directly at the official Grants.gov listing before applying.
Who qualifies
How to apply
Questions people ask
Is this a grant or a loan?
It is a grant, funded by the National Institutes of Health.
Do I have to repay the funding?
No, grants generally do not require repayment when used per award terms, though specifics should be confirmed at the source.
Who is eligible to apply?
Only U.S. small business concerns, as defined by the SBA, that partner with a nonprofit research institution.
Can foreign companies apply?
No, foreign organizations and non-domestic components of U.S. organizations are not eligible.
How much funding can I get?
The specific award floor, ceiling, and amount were not provided; confirm at the official source.
What is the application deadline?
April 5, 2027, 12:00 AM EDT.
Where do I apply?
Through the official Grants.gov listing at https://www.grants.gov/search-results-detail/359757.
What does this grant fund?
It funds feasibility studies and later-stage R&D to help bring scientific innovations to market through small business and nonprofit research partnerships.
Which states are eligible?
All U.S. states are eligible.
What category of funding is this?
It falls under research and technology (R&D) funding.
Is a nonprofit research partner required?
Yes, the STTR structure requires collaboration between a small business and a nonprofit research institution.
Is the grant income taxable?
This was not specified in the available data; confirm at the official source.
What phases does this grant cover?
It includes the R41 phase (feasibility studies) and R42 phase (later-stage R&D).
Who administers this program?
The National Institutes of Health administers this STTR grant.
Opportunity number: PA-27-102. Source: grants.gov. GetFundedUSA is independent and not affiliated with National Institutes of Health; always confirm current deadlines, amounts and eligibility on the sponsor's own page before applying.